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EDN (16 May 2002), Going nonlinear, Howard Johnson
Spice is grand for solving circuits that have complicated topologies or include nonlinear elements. If, however, you are working with a simple, linear circuit, you might question whether Spice is best.
For example, suppose you are designing a 2.5-Gbps serial-communications channel terminated at both ends. Your 100Ω output-impedance driver is a highly linear creature. So is your load. Simulations of this circuit therefore produce the same output whether you use a linear-analysis tool or Spice.